Organ-on-a-Chip Image Competition
Thank you to all that entered this year's photo competition.
Congratulations to the winners:
University of Glasgow
"This image shows a spheroid containing hepatocytes derived from human pluripotent stem cells and cultured for up to 7 days. Fibronectin (red), PDX1 (yellow) and collagen 1 (grey). This liver spheroid can be co-cultured to develop a 3D in-vitro model of pancreatic ductal adenocarcinoma metastasis to the liver."
£100 voucher and Lab on a Chip subscription
Stefania Di Ciò
Queen Mary University of London
"Confocal image of a cardiac spheroid co-cultured with HUVECs in a fibrin gel in a microfluidic device. Red= cTnT (cardiac spheroid); White = CD31 (vasculature); Green = NG2 (mural cells); Blue = DAPI"
"3D printed retinal vasculature"
"A 3D model of the human retinal vasculature printed in resin. The original image was generated by Pfefer et al in their paper 'Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging' 10.1117/1.JBO.20.12.121312"
King's College London
"hiPSC undifferentiated spheroid (OCT4, green and DAPI, Blue)."
Imperial College London
"Triple Negative Breast Cancer cells attachment on novel bio-chips for real-time detection of tumour acidification (by Melina Beykou and Lewis Keeble)"
"Our aim is the development of a Lab-on-Chip device which uses an Ion-Sensitive Field Effect Transistor (ISFET) array on a CMOS platform for the real-time detection of acidification in the tumour microenvironment. This image illustrates the attachment of triple negative breast cancer cells onto the ISFET array."
Blizard Institute, QMUL
"Terminally Differentiated Human Skin Equivalents"
"Terminally Differentiated Human Skin Equivalents grown in Collagen-Matrigel"
CN Bio Innovations
"Livering the Dream - Liver-on-a-Chip"
"Liver-on-a-chip scaffold cultured in the CN Bio PhysioMimix multi-organ microphysiological system. Primary hepatocytes were cultured for 4 days before being cocultured with a lung-on-a-chip model for a further 4 days. Scaffolds were fixed and stained for albumin (yellow), alpha-tubulin (green), actin (magenta) and nuclei (blue)."