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Queen Mary University of London
Organ-on-a-Chip Technologies Network

Mr Timothy Hopkins

PhD Student

Department  Institute of Science and Technology in Medicine
  Keele University
Telephone  01691 404699

My Interests

 Osteoarthritis, Cartilage, Subchondral Bone, Co-Culture, MSCs, Chodnrocytes

I am interested in the in-vitro modelling of the knee joint, using multiple cell types to mimic the joint environment in various health states. We have developed an indirect co-culture model in which characterised cells from regions of the subchondral bone, with and without pathological changes, are cultured with donor-matched chondrocytes, to investigate the effect of bone health on the cartilage forming capacity of the chondrocytes. I am hoping to use the network to build on my knowledge of the in-vitro modelling of disease and identify new methods for doing so.